THE lachrymal gland in mammals has acinar tissue leading to ducts lined with columnar epithelium showing no regional differentiation. The Na/K ratio of an established secretion shows no alteration in ...

Aims Mineralocorticoid receptor (MR) antagonists improve cardiovascular outcomes in patients with heart failure complicating acute myocardial infarction (AMI) and in chronic heart failure. It is ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Mineralys' lorundrostat, a selective aldosterone synthase inhibitor, shows promise in treating resistant hypertension with fewer side effects compared to current MRAs. Upcoming catalysts include ...

Credit: Getty Images Investigators report promising results from a phase 2 trial of an investigational aldosterone synthase inhibitor. Combining the aldosterone synthase inhibitor with empagliflozin ...

Please provide your email address to receive an email when new articles are posted on . BI 690517 dose-dependently reduced urine albumin-to-creatine ratio, showing a potential albuminuria reduction.

The coronavirus disease 2019 (COVID-19) pandemic caused millions of deaths throughout the world, which has provoked intense research into the pathogenetic mechanism behind this disease. A new study ...

Noninferiority trial favored amiloride as an alternative to spironolactone in lowering home systolic blood pressure (SBP) for people with resistant hypertension. Twelve weeks into the trial, mean home ...

AUGUSTA, Ga. (Oct. 18, 2021) – Another difference between females and males appears to be a key mechanism in how they become hypertensive, scientists say, and consequently which antihypertensives ...