The synthesis and subsequent functionalisation of amides have emerged as pivotal areas in modern synthetic chemistry, enabling the direct conversion of these otherwise inert functional groups into ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

Amides are among the most ubiquitous functional groups in organic chemistry, forming the backbone of peptides and playing a vital role in pharmaceutical, synthetic and materials chemistry. Their ...

Amide bonds are common in drugs because they are chemically stable, form readily and are biocompatible. They also help ...

Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...

Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a biotech that synthesizes challenging peptides, announced today that it has begun commercializing its novel peptide manufacturing platform. The ...

Chemical structure of imatinib, a precision cancer drug containing an amide bond. Xiaoguang Lei and his team used their engineered enzyme to streamline the synthesis of imatinib, a landmark cancer ...

Professor Pei-Qiang Huang's research group at Xiamen University recently reported the first reduction-cross-coupling reaction of aliphatic tertiary ...