Amide bonds are common in drugs because they are chemically stable, form readily and are biocompatible. They also help ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

A catalyst that effectively converts amides to amines at low temperature under low hydrogen pressure has been demonstrated by a team of researchers. Amines are vital in nature; for example, amino ...

The amide bond can be activated for cleavage under mild, neutral conditions by chemical derivatization, a British group has demonstrated (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201107117). Amide ...

Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...