Catalytic amination reactions have emerged as a transformative tool in modern synthetic chemistry, enabling the efficient construction of carbon–nitrogen bonds that are pivotal in pharmaceuticals, ...

Carbon dioxide (CO 2) electrocatalytic reduction driven by renewable electricity can solve the problem of excessive CO 2 emissions. Since CO 2 is thermodynamically stable, efficient catalysts are ...

Led by Director CHANG Sukbok, scientists from the Center for Catalytic Hydrocarbon Functionalizations within the Institute for Basic Science (IBS) have made a breakthrough in understanding the ...

The site-selective amination, which links arenes to aromatic nitrogen heterocycles or ammonia, offers chemists an easy way to make derivatives of aromatic compounds. Such a transformation could be a ...

Many approved drugs contain benzylic nitrogens, which can influence bioactivity substantially. A new catalytic reaction that adds amine groups to benzylic C–H bonds more selectively than was ...

This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...

Researchers have made a groundbreaking discovery by identifying the structure and reactivity of rhodium-acylnitrenoid intermediates in catalytic hydrocarbon amination reactions. By studying ...