Congenital dyserythropoietic anemias (CDAs) are inherited disorders primarily characterized by failure of the erythroid lineage to effectively differentiate into red blood cells. CDAs are classified ...

Scientists have just discovered how the protein Asf1 ensures the correct (re)organization of duplicated DNA. During DNA replication, all the information in the mother cell must be transmitted to the ...

Histone chaperones and chromatin remodelers control nucleosome dynamics, which are essential for transcription, replication, and DNA repair. The histone chaperone Anti-Silencing Factor 1 (ASF1) plays ...

Fluidigm Corporation has announced that the Fluidigm TOPAZ ® system has played a major role in the structure determination of Anti-Silencing Function 1 (Asf1) with histones H3/H4. Asf1 is a highly ...

Scientists have described how a genetic duplication that took place in the vertebrate ancestor some 500 million years ago encouraged the evolution of the ASF1b gene; a gene essential for proper cell ...