Business Insider

I got tested for the BRCA2 gene mutation after my mom was diagnosed with breast cancer. A simple test gave me peace of mind.

I was 18 when my mom was diagnosed with breast cancer. It altered the trajectory of my second year at college and changed how I viewed my mom, whom I naively thought was exempt from harm. She knew ...
ascopubs.org

BRCA1 and BRCA2 Mutation Frequency in Women Evaluated in a Breast Cancer Risk Evaluation Clinic

Multicenter Phase II Study of a 28-Day Regimen of Orally Administered Eniluracil and Fluorouracil in the Treatment of Patients With Anthracycline- and Taxane-Resistant Advanced Breast Cancer PURPOSE: ...
Labroots

New Understanding of BRCA2 Mutation-Driven Mechanism Could Inform Anti-Cancer Drug Development

Inherited mutations in the gene BRCA2 significantly increase the risk of carriers to breast and ovarian cancers. BRCA2, a crucial player in the body's DNA repair system, aids in repairing damaged DNA.
Yahoo

Study identifies risk potential for thousands of mutations of a cancer gene

Add Yahoo as a preferred source to see more of our stories on Google. FILE PHOTO: A radiologist examines breast X-rays after a cancer prevention medical check-up at the Ambroise Pare hospital in ...
Medical Xpress

BRCA-mutation carriers with history of early-onset breast cancer may benefit from risk-reducing surgery

Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral risk-reducing mastectomy (RRM) and/or a risk-reducing ...
The Atlantic

The Cancer Gene More Men Should Test For

Sign up for Being Human, a newsletter that explores wellness culture, mortality and disease, and other mysteries of the body and the mind. “It’s a branding ...
News Medical

Study sheds light on origins of breast cancer in people with BRCA2 mutations

A pioneering study led by Professor Ashok Venkitaraman from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and Dr Mona Shehata from the University of ...
Hosted on MSN

BRCA Mutations Hike Risk of Rare Breast Implant-Associated Lymphoma

Patients with BRCA-mutant breast cancer had a significantly higher risk of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL), a large cohort study showed. BRCA1/2 mutations conferred ...
Nature

The coexistence of a BRCA2 germline and a DICER1 somatic variant in two first-degree cousins suggests their potential synergic effect

BRCA1 and BRCA2 are involved in DNA damage response, specifically in the homologous recombination repair pathway. Cells with pathogenic variants in BRCA genes are error-prone at the DNA level and ...
Medical Xpress

BRCA1 gene mutation may increase the risk of impaired fertility, study shows

People with a BRCA1 gene mutation, which increases breast and ovarian cancer risk, are also at increased risk of impaired fertility, Monash University-led research has confirmed in preclinical models ...
EurekAlert!

BRCA-mutation carriers with a history of early-onset breast cancer may benefit from risk-reducing surgery

SAN ANTONIO – Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral risk-reducing mastectomy (RRM) and/or a risk-reducing ...