The inherited mutation substantially increases the chance of developing lung cancer, including in people who don't smoke.

A rare genetic mutation could help to explain why some people who don’t smoke still develop lung cancer.

Lung cancer is so closely associated with smoking that people who have never smoked may assume their risk is extremely low.

C EGFR T790M gene variant face roughly 25 times the lung cancer risk of noncarriers, according to the largest-yet study of ...

The gene is found predominantly in Southern Appalachia and may be one of the most powerful cancer-risk mutations ever found.

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals. These are the findings published on 3 December in ...

Some 17 million Americans are living with genetic mutations tied to an increased risk of getting cancer, Cleveland Clinic researchers warned Monday. And the more than 3,400 mutations identified – ...

Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different genetic paths. A new study shows that these differences can sometimes be traced ...

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give ...

KRAS mutations lead to excessive cell growth due to alterations in the KRAS gene. They are present in a significant percentage of non-small cell lung cancers (NSCLC). Diagnosis involves testing ...

A genetic mutation that raises lung cancer risk was much more common among those born in Southeastern states than elsewhere ...