Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...

Teleost fish possess a sophisticated immune system in which cytokines act as central mediators of both innate and adaptive defence mechanisms. These small secreted proteins, including interleukins, ...

Researchers provide essential insights on the molecular activation of the MAP kinase p38?, the final switch triggering the inflammatory response. Inflammation is a cellular coping mechanism when ...

Cytokines contribute to the antitumor response through several key pathways and interactions with different immune cells. These include the following: (a) Natural killer (NK) cells: Cytokines such as ...

Researchers have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for ...

Researchers at Toho University have uncovered a previously unrecognized mechanism controlling how dying cells release the ...

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been implicated in ...

The job of your immune system is to protect your body from harmful foreign substances and keep you healthy. But sometimes your immune system does your body more harm than good. A cytokine storm occurs ...

Cancer immunotherapy has advanced significantly in recent years, dramatically improving patient prognosis and survival. The majority of cancer immunotherapy research currently focuses on the first T ...

People often get immunotherapy as a treatment for cancer. These immunotherapy treatments can be effective, but they may cause your immune system to have an unnatural response. Your body, as a result ...

Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an ...