The roundworm Caenorhabditis elegans is revealing the molecular glitch behind a rare brain disorder. In lissencephaly – Greek for "smooth brain" – the cerebral cortex lacks characteristic convolutions ...

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make ...

In an exciting scientific first, researchers at the Allen Institute successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice. These are a ...

Aspen Oothoudt said doctors made the same recommendation "several times" after seeing her scan, but her heart told her ...

For the first time Monash University researchers used the technique to uncover degenerative brain processes in people with the faulty HD gene, decades before symptoms arise. The neurological condition ...

A team has identified a molecular cellular mechanism that is linked to microencephaly, a condition in which a baby's head is much smaller than expected. Nonsense-mediated RNA decay, or NMD, is an ...

NEW YORK (AP) – A lab study has found that Zika can infect embryonic cells that help form the brain, adding to evidence that the virus causes a serious birth defect. The mosquito-borne virus is ...

Summary: Researchers unmasked the hidden mechanisms that allow the Ebola virus to survive undetected inside the human central nervous system for months or years. The international investigation ...

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA. They found that the defect is highly sensitive to an ...