Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.

New findings identify CASP4/11 as detrimental to inflammation and coagulopathy associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Researchers recognize CASP4/11 as ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...