When a new memory forms the brain undergoes physical and functional changes known collectively as a “memory trace.” This memory trace represents the specific patterns of neuronal activity and ...

When we form a new memory, the brain undergoes physical and functional changes known collectively as a "memory trace." A memory trace represents the specific patterns of activity and structural ...

When cells are healthy, we don't expect them to suddenly change cell types. A skin cell on your hand won't naturally morph into a brain cell, and vice versa. That's thanks to epigenetic memory, which ...

Our experiences leave traces in the brain, stored in small groups of cells called "engrams". Engrams are thought to hold the information of a memory and are reactivated when we remember, which makes ...

Anyone who has ever tried to get rid of a few extra kilos knows the frustration: the weight drops initially, only to be back within a matter of weeks—the yo-yo effect has struck. Researchers at ETH ...

Memories don’t live everywhere in the brain. They’re stored in small clusters of neurons called engrams that fire again when a memory is recalled. Research over the past decade has mapped these memory ...

Astrocytes are abundant non-haematopoietic cells of the central nervous system (CNS) that have important functions in health and disease 9,10,11. Astrocytes participate in key processes that are ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...

Neurons have variable levels of chromatin compaction, shown as different shades of red. The less compact a neuron, the more likely it is to be recruited into the memory trace (green). When we form a ...

In an important study for understanding how memories are made, cientists show that the flexibility of chromatin -- packaged DNA inside the cell -- plays a crucial role in 'deciding' which neurons are ...