Context: Fatal familial insomnia (FFI) is a genetically transmitted neurodegenerative prion disease that incurs great suffering and has neither a treatment nor cure. The clinical literature is devoid ...

The first sign of my father’s decline came at his lunchtime basketball game. At 66-years-old, he’d always been healthy and active. Then he tripped during a game. A few weeks later, he forgot where to ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access information on a device and to provide personalised ads and content, ad and ...

This is an archived article and the information in the article may be outdated. Please look at the time stamp on the story to see when it was last updated. Can’t sleep? It could be worse, you could be ...

Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic ...

Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of muscle groups and/or entire limbs. The three major phenotypes of genetic ...

Disclosure: Joyce Schenkein, PhD, has disclosed no relevant financial relationships. Disclosure: Pasquale Montagna, MD, has disclosed no relevant financial relationships.