A new study is the first to show that the Parkin gene is turned on when cells are exposed to environmental insults that cause free radical formation and cataract formation. Researchers have discovered ...

Mopping up free radicals with antioxidants was the rage in the 1970’s; people were taking large, sometimes massive doses of various general antioxidants, including vitamins and minerals, to try to ...

The Aβ-binding alcohol dehydrogenase (ABAD) forms a complex with Aβ in mitochondria, promoting leakage of free radicals, mitochondrial dysfunction, and cell death, according to a combined ...

MONTEVIDEO, Uruguay, March 24, 2014 /PRNewswire/ -- Researchers at The Center of Free Radical and Biomedical Research at Facultad de Medicina, Universidad de la Republica in Uruguay today announced ...

After a brain hemorrhage, neural support cells called astrocytes enhance healing by transferring their mitochondria to damaged neurons. The healthy mitochondria stimulate the production of a free ...

Oxygen-consuming organisms obtain energy through cellular respiration, which is the transformation of carbohydrates and oxygen into carbon dioxide and water. This process also produces toxic oxygen ...

Sigma-1 receptors (Sig-1Rs) are endoplasmic reticulum (ER)-resident proteins known to be involved in learning and memory. Dendritic spines in hippocampal neurons play important roles in ...

Deferoxamine mesylate, bovine SOD (EC 1.15.1.1), SIN-1, SNAP, MTT, catalase (EC 1.11.1.6), quercetin, rutin, sodium salicylate, and glutamate were purchased from ...

The novel synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid (AHPN/CD437) has been proven to be a potent inducer of apoptosis in a variety of tumor cell types. However ...

Although mutations in the PARK2 gene that encodes the Parkin protein are associated with developing early-onset Parkinson's disease (PD), much remains to be discovered about how Parkin functions in ...