Paul Melançon, 57, tried dozens of antidepressants across multiple drug classes — first alone, then in combinations that his doctors hoped might work better. None provided lasting relief from his ...

Researchers say they’ve been able to measure recovery from treatment-resistant depression through brain scans — a crucial step toward quantifying the impact of therapies on a condition whose progress ...

It can be challenging to create a treatment plan for depression. This is especially true for patients who aren't responding to conventional treatments and are undergoing experimental therapies such as ...

Researchers have found that even after recovery, individuals who previously experienced depression may retain a heightened sensitivity to negative cues and face challenges in regulating responses to ...

A team of leading clinicians, engineers, and neuroscientists has made a groundbreaking discovery in the field of treatment-resistant depression. By analyzing the brain activity of patients undergoing ...

Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) is an evidence-informed treatment utilizing Cognitive Behavioural Therapy (CBT) treatment principles. UP has demonstrated ...

Patients with treatment-resistant depression (TRD) experience a wide variety of debilitating symptoms, including persistent negative mood, anhedonia, psychomotor retardation and suicidal thoughts.

Using a novel deep brain stimulation (DBS) device capable of recording brain signals, researchers have identified a pattern of brain activity or "biomarker" related to clinical signs of recovery from ...

Patients with newly diagnosed fibromyalgia who had prominent symptoms of depression and anxiety had more severe disease and a poorer response to initial treatment than those without prominent symptoms ...

It was hoped as a Depression-era summer turned into a more optimistic autumn of 1933 that a parade would lead to purchases and prosperity. "Canton's Big Parade Speeds Up Recovery," said a bold and ...

It can be challenging to create a treatment plan for depression. This is especially true for patients who aren’t responding to conventional treatments and are undergoing experimental therapies such as ...

New research in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging shows that the brain of individuals who have recovered from depression retains a heightened sensitivity to negative cues, ...