A mysterious and unpredictable group of side effects from modern medications called idiosyncratic drug reactions likely will persist as a major health care problem unless there is a dramatic increase ...
Phenotypes Acute hepatic necrosis, serum enzyme elevations, sinusoidal obstruction, acute fatty liver, nodular regeneration Acute hepatocellular hepatitis, mixed or cholestatic hepatitis, bland ...
The pathogenesis of idiosyncratic “hypersensitivity” reactions to the sulphonamides is thought to be mediated by reactive intermediates. We have previously demonstrated dose-related toxicity of ...
Adverse drug reactions (ADRs) encompass a spectrum of harmful or unintended responses to medicinal agents, broadly classified into predictable, dose-dependent events and unpredictable, idiosyncratic ...
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