Interleukin-9 is a pleiotropic cytokine associated with allergic inflammation 1 and is a therapeutic target in patients with asthma. Its expression and that of the interleukin-9 receptor are greater ...
CI denotes confidence interval, and SNP single-nucleotide polymorphism. Sequencing reads were aligned to the hg19 reference genome. A SIFT (sorting intolerant from tolerant) score of less than 0.05 ...
"Boosting the immune defense: Interleukin-2 promotes fate decisions in CD8 T cells for long- or short-term immune protection." ScienceDaily. www.sciencedaily.com / releases / 2022 / 02 / ...
Interleukin (IL)-1 is a prototypic proinflammatory cytokine. It is produced by numerous cell types (i.e., macrophages, synoviocytes, endothelial cells, chondrocytes, osteoclasts) and is found in ...
B cells are known to generate antibodies through two different responses—an "emergency response" and an "everything is okay, let's prepare for the future response," says Mark Shlomchik, UPMC Professor ...
However, imbalances of IL-6 — too much or too little — can cause disease, even in the absence of infection. Excess IL-6 is central to the pathogenesis of inflammatory reactions like rheumatoid disease ...
The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been implicated in ...
A pleiotropic cytokine central to the regulation of T-cell responses, interleukin 2 (IL-2), plays an essential role in a huge range of other immune modulatory actions. Image Credit: Sino Biological ...
The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...
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