The Bills beat the Patriots 24-21 thanks to the performance from starting running back James Cook along with timely plays made by the defense. Cook ran the ball 11 times for 100 yards and one touchdown while also catching three passes for 26 yards and another touchdown, showing his ability to affect the game on the ground and through the air.

The Buffalo Bills defeated the New England Patriots in their first matchup against each other this season. Although the final score was 24-21 with Buffalo on top to finish, the Bills didn’t get their feet under themselves right away.

The Buffalo Bills must keep their foot on the gas. Despite being a long shot to supplant the Kansas City Chiefs for the No. 1 seed in the AFC, there's more at stake.

The Buffalo Bills are still in the mix for the No. 1 seed in the AFC playoff picture. Buffalo shook off injuries, miscues and a subpar performance from Josh Allen to eke past the New England Patriots 24-21 and stay in the race for a first-round bye and home field advantage throughout the conference postseason.

If the Chiefs and Bills end up with the same record, Buffalo owns the head-to-head tiebreaker on Kansas City. The Bills and No. 1 seed and the bye week that comes with that in Round 1 of the postseason could still be alive.