49ers-Rams roundtable: Who's stopping Matthew Stafford? Can S.F. pull off the upset?

The Chronicle's coverage team weighs in as the San Francisco 49ers (6-3) are preparing to host their division-rival Los ...

49ers' Brock Purdy to miss sixth straight start, could play backup role against Rams

SANTA CLARA, Calif. — Quarterback Brock Purdy will miss his sixth straight start for the San Francisco 49ers with a toe ...

49ers missing another defensive starter vs. Rams in NFC West showdown; Purdy won't start

The San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee ...

49ers QB Mac Jones again gets starting nod for Rams game

While quarterback Brock Purdy slowly works his way back from injury, the 49ers will once again turn to Mac Jones as the ...

The 49ers might not play Brandon Aiyuk at all this year

Case in point: the latest discourse from 49ers insiders Tim Kawakami and Matt Barrows on San Francisco’s star wideout, ...

5 San Francisco 49ers who need to step up to beat the Los Angeles Rams

The San Francisco 49ers have been underdogs three times already this year and have lost twice. Their only win was over the ...