Integrating Digital Holographic Microscopy with fluorescence techniques enhances live-cell imaging, preserving cellular ...

Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods rely on adhesive or mechanical forces to hold and scan cells, which limit ...

Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Measurement software Measurement functions (2D, 3D, Time-lapse, Map imaging), Viewing measurement and sampling data, Reporting functions (Image data, Video data), Whole-cell sampling, Intracellular ...

A new kind of microscope is giving scientists a way to watch life inside cells with a clarity that feels almost unfair. Instead of choosing between seeing big structures or tiny particles, researchers ...

Light microscopy is the only way in which we can look inside a living cell, or living tissues, in three dimensions. An electron microscope only gives a two-dimensional view, and the organic sample ...

A robust, image-based neurotoxicity assay helps scientists streamline subcellular neuronal analysis with live-cell dyes and high-throughput automated microscopy. Neuronal cell culture models allow ...

CAPTION: (Top) Condensins seem to act as a molecular crosslinkers to make loops. (Bottom, left) Condensins (red) locate around chromosome center. (Bottom, right) Nucleosomes around the periphery ...

Imaging live cells without disrupting their natural behavior or damaging their structures is one key challenge in biomedical optics, and has been tackled in multiple ways. A project at NIST has now ...

A new hybrid microscope for the first time allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. (Nanowerk ...