Loss of major histocompatibility complex class I (MHC-I) is frequently observed in cancer and is associated with the escape of cancers from CD8 + T cell-mediated killing. Therefore, it is important to ...
The major histocompatibility complex (also known as the HLA complex in humans) has a key role in shaping cellular adaptive and innate immune responses. It is a multigenic chromosomal region that, in ...
The major histocompatibility complex (MHC) region plays a crucial role in immune function; therefore, any genetic or epigenetic polymorphisms within the MHC locus may result in various diseases, as ...
Interferon signaling and outcomes in triple-negative breast cancer (TNBC) in FinXX, CALGB 40603 (Alliance) and real-world clinico-genomic data.
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