Prior to updates showing Week 15’s games, the Vikings are No. 22 in DVOA and will likely move into the teens after the win, while the Giants are No. 26 and dropping. If this line moves to 3.5, you’ll have the chance to arbitrage and middle it, with the chance both win if the Vikings win by a field goal.

Two playoff spots were clinched in Week 15 of the 2025 season, as the Denver Broncos and Los Angeles Rams both orchestrated come-from-behind wins to punch their

The Rams won big in Week 14, and that was important for Matthew Stafford's MVP odds. Stafford is back to being the betting favorite to win MVP after throwing for 281 yards and three touchdowns in a 45-17 blowout of the Cardinals. Stafford is -175 to win MVP. Drake Maye, last week's favorite who had a bye in Week 14, is +200.

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Sunday Night Football between New England Patriots and Baltimore Ravens.

Get the opening NFL Week 15 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Dec. 11, 2025.

The Dallas Cowboys host the Los Angeles Chargers in Week 16, with the opening odds showing rare faith in America's Team as their NFL playoff hopes dwindle.

The NFL Week 15 schedule is full of playoff implications. Among them is the AFC West matchup between Justin Herbert and the Los Angeles Chargers

NFL Week 16 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Atlanta Falcons and Arizona Cardinals.