Week 1 of the 2025 NFL season was pretty good to the NFC West. Well, it was good to all but one team. The division went 3-1, and that one loss was inevitable because there was a divisional matchup in Week 1. The only team to lose was the Seattle Seahawks.

A lot can go into determining how any given NFL season will play out. A lot of these things NFL teams can control, like personnel both on the field and in the front office, and coaches doing their jobs at a very high level. Other things, like injury luck and strength of schedule, are things NFL teams cannot control.

Newsweek Sports Betting Editor Tyler Everett makes his early picks against the spread for every Week 2 matchup.

These are the questions Kansas City will answer against Philadelphia in Week 2 — and much like Baltimore-Buffalo in Week 1 it is the toughest pick of the week. By the way, the Chiefs have not started 0-2 since Reid's second season in 2014.