Necroptosis and pyroptosis are two forms of programmed cell death with a common feature of plasma membrane rupture. Here we studied the morphology and mechanism of pyroptosis in comparison with ...

Why does pyroptosis take place? Pyroptosis is a form of programmed cell death that occurs during intracellular pathogen infection, as part of the body's antimicrobial response. Cell-surface receptors ...

Pyroptosis is a proinflammatory type of cell death that is associated with gasdermin-mediated membrane hole formation, as well as cell enlargement and lysis. Pyroptosis plays an important role in both ...

Identification of Pancreatic Cancer Germline Risk Variants With Effects That Are Modified by Smoking A sum of 921 samples were collected from three independent data sets. We obtained ...

PANoptosis, an emerging concept in immunology, refers to a form of programmed cell death that integrates various signaling ...

Cytokine release syndrome, a side effect of an immunotherapy used to treat leukemia and lymphoma, appears to be caused by the way the intervention kills the tumor cells, according to a mouse study ...

Cancer immunotherapy, a pivotal shift in combating cancer, harnesses the immune system to target malignant cells. Although it ...

Previous research has shown that cytotoxic lymphocytes rely on gasdermin-mediated pyroptosis to kill tumor cells. Pyroptosis appears to be closely involved in anticancer immune response and has ...