Reciprocal translocations (RecT) and Robertsonian translocations (RobT) are among the most common chromosomal abnormalities that cause infertility and birth defects. Preimplantation genetic testing ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 23 (Jun. 6, 2006), pp. 8786-8791 (6 pages) The telomere and centromere are two specialized structures of ...

We investigated six Robertsonian translocations, including two cases of rob(13q14q), one of rob(14q21q), one of rob(13q22q), and two of rob(21q21q), by means of fluorescencein situ hybridization (FISH ...

Robertsonian chromosomes are associated with infertility and Down syndrome, now cutting-edge DNA sequencing technology has unveiled the first comprehensive picture of their genetic rearrangements.

When couples have trouble conceiving a baby or lose a pregnancy, they often undergo routine tests, which can turn up a shock: One of the prospective parents may be missing a chromosome. The most ...

A 23-year-old man was referred in February 2006 because of AML. The karyotype of BM leukaemic cells was 47,XY,+4. The patient underwent induction chemotherapy and CR was obtained. Cytogenetic analysis ...

Robertsonian chromosomes are large chromosomes that form when the long arm of a chromosome breaks and fuses with another chromosome. They are the most common type of chromosome rearrangement in humans ...

Changes in either chromosome structure or number can occur during cell division. Each human has 46 chromosomes, 22 pairs of autosomes and 1 pair of sex chromosomes (XX: female or XY: male). During ...

Hailey Avery was overjoyed as a clear blue line appeared on the pregnancy test. Despite experiencing hormone issues since the age of 15 - including painful menstrual cycles and side effects from the ...

Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes ...

In about one out of every 800 people, two chromosomes fuse together to form an unusual bond. These are known as Robertsonian chromosomes. It's a mystery that has long stumped scientists. Now, ...