An ESPN analyst believes the 49ers can make noise in the playoffs, but one fatal flaw could derail San Francisco's postseason hopes.

Everything you need to know about the Rams vs. San Francisco 49ers in Week 10 of the NFL season, including how to watch and a prediction on who will win.

NFL Week 15 odds, picks, predictions, TV channel, streaming for Thursday Night Football game between Los Angeles Rams and San Francisco 49ers.

The 49ers can clinch a playoff berth in Week 16 with a win over the Colts — or with help before kickoff. Here's how San Francisco gets in.

The stakes are immensely high in tonight's NFC west divisional game between the San Francisco 49ers and Los Angeles Rams. Neither team can afford a loss with playoff implications on the line. For the 49ers, a loss would mean they likely do not win the ...

The San Francisco 49ers are playing the Tennessee Titans on Sunday, but they could benefit from some other games going certain ways.

Rams star receiver Davante Adams is listed as doubtful due to two leg injuries for Los Angeles' NFC West showdown with the Seattle Seahawks on Thursday night.

The Los Angeles Rams travel to Seattle looking to shine under the primetime lights and potential rain as they face the Seahawks. Watch this week's game trailer in preparation for Thursday's kickoff at 5:15pm PT on Amazon Prime Video.

San Francisco 49ers quarterback Brock Purdy looked like a basketball player with an impressive touchdown pass on Sunday.