Current single-cell RNA atlases largely capture polyadenylated transcripts while missing critical regulatory layers from noncoding RNA. To address this, we develop a generalizable framework that ...

Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool to record and dissect gene expression of individual cells in tissues. Compared to bulk RNA-seq, where RNAs from all cells in a ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

SPT Labtech, a global leader in the design and development of laboratory automation and liquid handling solutions, and Alithea Genomics, a pioneer in the field of large-scale RNA sequencing and ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and the molecular events within them are dynamic, and developmental processes, ...