Click for The Sporting News' fantasy running back Week 10 rankings. Find the best RB starters, bye-week replacements, and top sleepers at the position.

Two rookies and four veterans make our list of running backs fantasy football managers need to leave on their bench in Week 10.

Here we will look at our NFL Fantasy Football Running Back Rankings entering Week 10 of the 2025 regular season.

We’re just days from the trade deadline, and almost halfway through the 2025 NFL Season! We have a few newcomers to the list this week, as a few backs have run their way onto the list. There’s been a bit of shakeup in the middle,

These running backs have great matchups, plenty of volume, and are featured heavily in their offense and thus will score a lot of fantasy points in Week 10.

The running back position wasn’t hit as hard by injuries last season, but we know how quickly things can change at one of the most physical positions in football. Fantasy football managers who stay prepared and know which backs are next in line for touches will always have an edge on the competition.

We’re close to halfway through the 2025 NFL season (how?!?), and we’re starting to see some of the running backs on our list cement their spots. We’ve also seen injuries cause several players to drop out of the top-10,

See the top projected fantasy running backs for Week 10. Our rankings highlight the best RB options to start in your fantasy football lineup.

As the season nears its midpoint, several quarterbacks continue to hold their spots in the Top 10 with strong performances week after week. Many wide receivers are improving steadily as well, and several running back units are beginning to find their rhythm.

Sunday was a very big day for big-play running backs in the NFL. Four different running backs ran for more than 100 yards and averaged more than 10 yards per carry on Sunday: Bills running back James Cook had 19 carries for 216 yards,

We're officially past the midway point of the 2025 NFL regular season, which means we're halfway to solidifying the early tiers of the 2026 NFL Draft order. The race for the No. 1 overall pick is still a three-team affair after Week 9,