A-to-I RNA editing, catalyzed by the adenosine deaminase acting on RNA (ADAR) family of enzymes, represents the most prevalent form of RNA editing in human cells. This process involves the conversion ...
The work proves that embryo editing is far from a clinical reality. But the experiment has sparked controversy nonetheless ...
Prime editing is capable of generating precise small DNA insertions, deletions or substitutions without double-strand DNA break intermediates 1,2,3 and has been widely used across biological research, ...
Megan covers the intersection of science and society. How is biomedical research funded? Who benefits? And how do new technologies reflect and shape our values? You can reach Megan on Signal at ...
Genetic editing holds promise to treat incurable diseases, but the most popular method—CRISPR—sometimes does more harm than good. A new study from University of California San Diego and Yale ...
Despite the copious demands of his administrative positions as the White House chief science advisor (and until last year, the director of the NIH), Francis Collins, MD, PhD, has continued to run a ...
CRISPR-based genome engineering revolutionized the gene-editing field by making experimental workflows considerably easier, faster, and more efficient than previous methods. Still, generating reliable ...