It appears the illness that limited San Francisco 49ers running back Christian McCaffrey won't have any effect on his Week 15 availability. McCaffrey was not on the Friday injury report, an indicator that he's good to go for Sunday's game against the Tennessee Titans at Levi's Stadium.

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action. Both teams are watching injuries in the wake of Week 15 games.

The Tennessee Titans face the San Francisco 49ers on Dec. 14. The 49ers added star RB Christian McCaffrey to the injury report (back) before the game.

The San Francisco 49ers added All-Pro running back Christian McCaffrey to their injury report Saturday with a back injury, but he should be "good to go" Sunday, according to a report.

The San Francisco 49ers have a bit of a scare to deal with as their star running back was limited in the team's second Week 15 practice.

San Francisco announced on Saturday afternoon that running back Christian McCaffrey has been added to the injury report as questionable with a back issue.

The San Francisco 49ers took another step towards severing ties with star wide receiver Brandon Aiyuk. According to The Athletic, the 49ers placed Aiyuk on the reserve/left squad list on Saturday, ending the receiver’s 2025 season and likely his tenure on the team.

The San Francisco 49ers didn't get the best possible news from their first Week 15 practice report, but it wasn't all bad.