Dre Greenlaw was on the field for four defensive plays before being sidelined with a calf injury in the 49ers' 29-17 loss to ...

The 49ers finished Sunday's game with, in essence, third-string offensive linemen playing left tackle and left guard. And ...

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 16 matchup ...

One day after his team was eliminated from postseason contention, 49ers coach Kyle Shanahan announced that left tackle Trent ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters during a Monday conference call, delivering multiple injury ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters during a Monday conference call, delivering multiple injury ...

The San Francisco 49ers could be gearing up for yet another tough offseason contract negotiation, this time with quarterback ...

The San Francisco 49ers entered Sunday's matchup against the Miami Dolphins without two key offensive contributors: running ...

The San Francisco 49ers will hold three full practices this week as they gear up for their Week 17 Monday night matchup ...

Despite an impressive individual effort—hauling in eight passes for 106 yards—George Kittle expressed clear frustration with ...

Brock Purdy's current NFL season has not mirrored the breakout success of last season when he set a single-season franchise ...

Former NFL cornerback Richard Sherman believes he knows exactly what the San Francisco 49ers need to focus on this offseason.