The Lions (12-2) have been hit hardest. Three key players suffered season-ending injuries Sunday and they lost another starter indefinitely. Forty-nine quarterbacks have started games this season as teams have turned to backups because of injuries or lack of production.

Buffalo Bills head coach Sean McDermott announced on Friday that starting cornerback Rasul Douglas will miss the Week 15 game at the Detroit Lions due to his knee injury suffered in the loss to the LA Rams last week.

ORCHARD PARK, N.Y. — The Buffalo Bills will be missing three key members of the secondary when they play the Detroit Lions on Sunday evening at Ford Field.

The Lions will officially be at full strength — relatively speaking — for their Week 15 showdown with the Bills at Ford Field.

The Bills are dealing with several injuries in their defensive backfield heading into Sunday's game against the Lions.

The Bills could be shorthanded at safety as both Taylor Rapp and Damar Hamlin are battling injuries. Edge: Lions The Lions felt they had to protect their beat-up defense and beat the Packers on offense last week, and they’ll need another big performance ...

The Buffalo Bills must turn to Plan B when it comes to the starting secondary on December 15 against the Detroit Lions. Starting safeties Taylor Rapp and Damar Hamlin are both amongst the Bills' gameday inactives. Both players, who were banged up last week ...

The Lions have revoked the season tickets of the fan who had ... but there was one significant change on their estimated injury report. Buffalo added safety Damar Hamlin (back/ribs) to the injury report as a non-participant on Thursday.

The Buffalo Bills are at risk of missing some key members of the secondary for their showdown with the Detroit ... Lions on Sunday, but could be getting some good news on another defensive front. The Bills have three starting defensive backs — safeties ...

Buffalo Bills safeties Damar Hamlin and Taylor Rapp, who were questionable for the road game against the Detroit Lions, were on the inactive list Sunday. Hamlin (back, ribs) and Rapp