During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the ...

Immune aging weakens protective responses against infection, cancer, and poor tissue repair, while increasing chronic inflammation and autoimmune risk. Domains of immune aging. With advancing age, ...

Studying mice, researchers have discovered that roseolovirus can trigger autoimmunity in a previously unknown way: by disrupting the process by which immune cells learn to avoid targeting their own ...

Autoimmunity When our bodies are exposed to a virus — or any infection — it recognizes proteins and other molecules on the invading virus as “not us.” Scientists refer to this as an antigen. We then ...

A single signaling pathway controls whether immune cells attack or befriend cells they encounter while patrolling our bodies, researchers at Stanford Medicine have found. Manipulating this pathway ...

The immune system defends the body against a wide range of internal and external threats. However, this versatility becomes an issue when immune mechanisms target host cells instead—a phenomenon ...

Summary of the research: This study revealed that T cells can discriminate between self- and neoself- antigens, and that neoself-reactive T cells are involved in causing autoimmune diseases. Osaka, ...

Please provide your email address to receive an email when new articles are posted on . van Trotsenburg and Mooij are pediatric endocrinologists at Emma Children’s Hospital, Amsterdam University ...

Please provide your email address to receive an email when new articles are posted on . Despite massive studies representing millions of participants that demonstrate associations between COVID-19 and ...