Most of the tasks that humans complete daily entail carefully coordinating movements and tracking progress made toward a ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...

A team led by Jason Shepherd at the University of Utah has identified the protein responsible for loading toxic tau into tiny ...

As knowledge of the development of neuronal pathways continues to grow, it also elucidates potential treatment modalities for neuronal degenerative diseases and injuries. Molecular and genetic ...

The ability to measure the connectivity of each neuron in a neural circuit has established large maps of neuronal pathways—the connectome. But the extent to which those connectivity measurements alone ...

Scientists have uncovered the intricate circuit cues behind neuronal cell maturation and migration, which is required for proper cognitive function. The journey of a thousand miles begins with a ...

Cell death in dementia has long posed a frustrating problem. Toxic proteins pile up inside neurons in Alzheimer’s disease and ...

Overview of the study. Researchers investigated the neural basis of how animals adapt to new environments and situations. To do this, they introduced a chemical ON/OFF switch in the orbitofrontal ...