Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Patients with an autoimmune or inflammatory disease (AIID) are at increased cardiovascular risk and may benefit more from statin therapy. In the FOURIER trial (Further Cardiovascular Outcomes Research ...

High-volume physical activity (PA) is associated with a higher prevalence of subclinical coronary artery disease (CAD). However, the clinical significance of subclinical CAD among high-volume ...

The advent of biventricular pacing (BVP) initiated the era of cardiac resynchronization therapy (CRT) to restore ventricular synchrony. However, BVP-CRT has a high nonresponder rate, ventricular ...

Cardiovascular disease remains a leading cause of morbidity and mortality in adults despite recent scientific advancements.

Introduction: Cardiovascular disease (CVD) risk differs across Asian subgroups possibly due to differences in hypertension burden. We characterized lifetime blood pressure (BP) trajectories for East ...

The growing morbidity, mortality, and health care costs related to heart failure (HF) underscore the urgent need to prioritize its primary prevention. Whereas a risk-based approach for HF prevention ...

BACKGROUND: Few middle-aged and older adults engage in regular leisure-time exercise. Incidental physical activity (IPA) ...

Request permissions for this article. Department of Medicine, UT Southwestern Medical Center, Dallas, TX (M.S.U.). Department of Medicine, Parkland Health and ...