Autoreceptors have an important role in neuronal homeostasis by regulating presynaptic functions in a feedback-inhibitory manner. There are three manifestations of autoreceptor function, reflecting ...
Cochlear outer hair cells (OHCs) influence sound-evoked cochlear vibration. They receive efferent, cholinergic feedback from medial olivocochlear (MOC) efferent neurons in the brainstem to regulate ...
An absence of autoreceptors on dopamine neurons may result in too much dopamine release, leading to schizophrenia symptoms. (Getty Images) Generations of studying the root cause of schizophrenia have ...
Please provide your email address to receive an email when new articles are posted on . Combination therapy that included an antagonist of presynaptic alpha2-autoreceptors appeared effective and safe ...
bReference National Center for Narcolepsy, Sleep Unit, Department of Neurology, Gui-de-Chauliac Hospital, University of Montpellier, Montpellier, INSERM U1061, France ...
Major depressive disorder (MDD) is the most prevalent mental illness contributing to global disease burden. Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are the first-line treatment for MDD, ...
ABSTRACT: Background: Mechanisms underlying overeating-induced obesity in post-menopausal woman include functional lack of 17β-estradiol dysregulating dopamine D2 receptors, thereby inducing food ...
eLife posts the editorial decision letter and author response on a selection of the published articles (subject to the approval of the authors). An edited version of the letter sent to the authors ...
† Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States ‡ Fishberg Department of Neuroscience, Icahn School of Medicine at Mount ...
Chronic selective serotonin reuptake inhibitor (SSRI) administration to rodents desensitizes or downregulates raphe 5-hydroxytryptamine 1A (5-HT1A) autoreceptors. We previously found elevated 5-HT1A ...
BACKGROUND AND PURPOSE The histamine H(3) receptor was identified as the autoreceptor of brain histaminergic neurons. After its cloning, functional H(3) receptor isoforms generated by a deletion in ...
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