Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery. Our immune system is armed with an array of defenses designed to detect and ...

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices. In ...

A University of Pittsburgh (Pitt) School of Medicine-led team has identified neuroinflammation as the key driver of the spread of pathologically misfolded proteins in the brain, and a cause of ...

Expression of a psoriasis-associated gain-of-function human CARD14(E138A) mutant protein in intestinal epithelial cells ...

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.

STARKVILLE, Miss.—A National Institutes of Health geneticist and a biomedical researcher and professor bring scientific insights—from human-canine genetic links to myths surrounding sharks and ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...