Scosglen is the northernmost region that you will be able to explore in Diablo 4, and contains 34 of Lilith's altars. Home of Donan of the Horadrim, this area you will typically explore during ACT 2 ...
In Diablo 4 the open world hides numerous treasures and secrets, but none are more important than Altars of Lilith. These hidden statues scattered across the map provide permanent account-wide buffs.