ahajournals.org

Thrombolysis for Ischemic Stroke Beyond the 4.5-Hour Window: A Meta-Analysis of Randomized Clinical Trials

A minority of patients with stroke qualify for intravenous thrombolysis (IVT) within 4.5-hour window. The safety and efficacy of IVT beyond this period have not been well studied. We performed a ...
Frontiers

Slope deformation prediction based on noise reduction and deep learning: a point prediction and probability analysis method

1 Hunan Provincial Communications Planning, Survey and Design Institute Co., Ltd., Changsha, China 2 Hunan Water Planning and Design Institute Co., Ltd., Changsha, China Gaussian-filter is a linear ...
eLife

Slowly evolving dopaminergic activity modulates the moment-to-moment probability of reward-related self-timed movements

Clues from human movement disorders have long suggested that the neurotransmitter dopamine plays a role in motor control, but how the endogenous dopaminergic system influences movement is unknown.
PNAS

Shortened tethering filaments stabilize presynaptic vesicles in support of elevated release probability during LTP in rat hippocampus

Long-term potentiation (LTP), a form of synaptic plasticity important for learning and memory, results in an increased probability of release of neurotransmitter from presynaptic vesicles. Prior work ...