Blood chemistry derangements from hydrochlorothiazide
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Blood chemistry derangements from hydrochlorothiazide
HCTZ is thiazide diuretic that inhibits reabsorption of Na in distal convoluted tubule → increased Na in collecting ducts → hyperactivity of Na-K exchanger → passive secretion of K ions into collecting duct → hypokalemia Other derangements: hypomagnesemia hyponatremia hypercalcemia Can ↓ incidence of kidney stones hyperuricemia Can ...
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